Research and application of micro-negative pressure control method in high-level biosafety laboratories

This paper presents the requirements on the building envelope of high-level biosafety laboratories, and briefly describes the principle of the micro-negative pressure control method. According to the actual situation of laboratory operation, the application of micro-negative pressure control method to filter replacement, final disinfection and emergency situations is discussed in depth, in order to provide references for the operation and maintenance of biosafety laboratories.